When your baby seems backed up, the gut is usually where the conversation starts.
NurtureBio is a daily synbiotic with five human milk oligosaccharides and four infant-friendly probiotic strains. Formulated to support a healthy gut microbiome and comfortable digestion in babies and toddlers ages 0 to 48 months.
Formulated with pediatric microbiome researchers · Third-party tested · Made for ages 0 to 48 months

Why little ones get backed up
Babies and toddlers get backed up for all kinds of reasons. A new formula. The first few weeks of solids. A round of antibiotics. A schedule change. A travel week. A growth spurt. Most of these have one thing in common, which is that they put pressure on a gut microbiome that is still figuring itself out during the first four years of life.
When the gut environment is balanced, the body tends to do what it already wants to do. When it gets thrown off, digestion slows down, stools get harder to pass, and your kid gets uncomfortable.
NurtureBio was formulated to support that gut environment with two of the ingredients babies are biologically wired to use, which are human milk oligosaccharides and bifidobacteria.
What is actually in the sachet
Five human milk oligosaccharides and four probiotic strains, in one daily synbiotic.
The prebiotic side of the blend
HMOs are special carbohydrates naturally abundant in breast milk. They feed the beneficial bacteria in your child's gut.
- 2'-FucosyllactoseThe most abundant HMO in breast milk for most mothers.
- DifucosyllactoseA fucosylated HMO that supports a breast-milk-like gut environment.
- Lacto-N-tetraoseA core HMO involved in early microbiome shaping.
- 3'-SialyllactoseA sialylated HMO involved in gut and brain development.
- 6'-SialyllactoseA sialylated HMO that helps nourish beneficial bacteria.
The probiotic side of the blend
These are the kinds of bacteria commonly found in the guts of breastfed babies.
- B. infantisA foundational bifidobacterium associated with the infant gut and softer stools.
- B. bifidumTwo well-studied bifidobacteria strains that support gut balance during early life.
- L. reuteriStudied in infants for its role in gut comfort and the gut barrier.
Curious about the specific strains? See our full formulation page
How a synbiotic supports comfortable digestion
Probiotics bring the beneficial bacteria
Four infant-friendly strains commonly found in breastfed babies.
HMOs feed those bacteria
Five human milk oligosaccharides modeled after the prebiotics in breast milk.
Together they support a balanced gut environment
Which is what the body uses to keep digestion comfortable and stools moving.
Made for the first four years
NurtureBio is formulated for babies and toddlers ages 0 to 48 months. Families often start using it during feeding transitions, after a round of antibiotics, when introducing solids, or as part of a daily routine that supports gut health from the start.
It mixes easily into breast milk, formula, water, or soft foods, depending on your child's age and what works for your day.
Why parents trust NurtureBio
Built with the researchers who study this
Our Scientific Advisory Board includes Dr. Jim Versalovic, Dr. Ardythe Morrow, Dr. David Newburg, and Dr. Diana Taft. They are among the most cited researchers in human milk and infant microbiome science.
Active research at the University of Cincinnati
We are conducting clinical research at the University of Cincinnati College of Medicine to advance the science of breast milk and infant gut health.
Built by parents who lived this
NurtureBio was started by Stuart and Christina Smith after their son fell from the 30th to the 6th growth percentile and went through five rounds of antibiotics in five months. What followed was chronic GI trouble, including the kind of stubborn constipation that has parents Googling at midnight. They could not find a product that took the infant gut microbiome seriously, so they built one with help from leading researchers in the field.
A daily synbiotic, one sachet at a time

NurtureBio Infant and Toddler Synbiotic
30 sachets. One per day. Mixes into breast milk, formula, water, or soft food.
Free shipping on subscriptions Third-party tested Made in France
Common questions from parents
Can NurtureBio help with my baby's constipation?
NurtureBio is a daily synbiotic formulated to support a healthy gut microbiome and comfortable digestion. It is not a laxative and it is not a treatment for constipation. Many families use it as part of a daily routine that supports gut health, especially during feeding transitions or after antibiotics. If your child is in pain, has gone several days without a bowel movement, or has any blood, fever, or vomiting, your pediatrician is the right next call.
What is the difference between a probiotic and a synbiotic?
A probiotic is a beneficial bacteria. A prebiotic is the food that beneficial bacteria eat. A synbiotic combines both in one product. NurtureBio combines four infant-friendly probiotic strains with five human milk oligosaccharides, which are the prebiotics naturally abundant in breast milk.
What ages is NurtureBio for?
NurtureBio is formulated for babies and toddlers ages 0 to 48 months.
How do I give it to my baby?
One sachet per day, mixed into breast milk, formula, water, or soft food. For younger babies who are still exclusively on milk, mixing into a small amount of breast milk or formula tends to work best.
How long until I notice anything?
Every child is different. Some families notice changes within the first couple of weeks. Others use NurtureBio as ongoing daily support rather than for a specific window. Gut health products tend to work best with consistent use over time.
Is it safe with breast milk and formula?
Yes. NurtureBio is formulated to mix into either, and it is also fine in water or soft food once your child is on solids. Always follow the directions on the package.
When should I call my pediatrician?
Call your pediatrician if your child has persistent or painful constipation, blood in the stool, fever, vomiting, poor feeding, or signs of dehydration. NurtureBio supports daily gut health and is not a substitute for medical care.
What are HMOs and why do they matter?
Human milk oligosaccharides, or HMOs, are special carbohydrates that are the third most abundant component of breast milk after fat and lactose. They are not digested by the baby. Instead, they feed the beneficial bacteria in the baby's gut, which is part of how breast milk shapes the infant microbiome. NurtureBio includes five HMOs in every sachet.
Support your child's gut, one day at a time.
A daily synbiotic for babies and toddlers, made with the ingredients their gut is biologically wired to use.
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