NurtureBio is a daily synbiotic with five human milk oligosaccharides and four infant-friendly probiotic strains. One sachet a day, made for ages 0 to 48 months.
Formulated with pediatric microbiome researchers · Third-party tested · Made for ages 0 to 48 months
Human milk oligosaccharides are special carbohydrates that make up the third most abundant solid in breast milk, after fat and lactose. The baby cannot actually digest them. That is the point. HMOs travel through the upper digestive tract intact and arrive in the lower gut, where they feed the specific bacteria that thrive in the infant microbiome.
There are more than 200 different HMOs identified in human breast milk so far. Researchers have spent the past two decades figuring out which ones do what, and the science has matured to the point where infant formulas now include one or two HMOs as standard. NurtureBio includes five. They were selected to represent the major structural classes found in breast milk and to support the bacteria most associated with early-life gut health.
A blend that reflects the structural diversity of HMOs in breast milk.
The most abundant HMO in breast milk for most mothers. 2'-FL has been studied extensively for its role in supporting beneficial gut bacteria and the developing immune system. It is also the HMO most commonly added to modern infant formulas.
A fucosylated HMO that pairs with 2'-FL in breast milk and supports a similar set of gut functions. Including DFL alongside 2'-FL gives the gut microbiome a closer match to the structural profile of breast milk than a single-HMO product can offer.
One of the core neutral HMOs in breast milk and a foundational substrate for Bifidobacterium infantis, the bifidobacterium most closely associated with the infant gut. LNT is part of how breast milk shapes which bacteria flourish in the early microbiome.
A sialylated HMO involved in gut development and studied in the context of brain development and cognitive function during early life. Sialylated HMOs make up a meaningful portion of total HMO content in breast milk.
The other major sialylated HMO in breast milk. 6'-SL helps nourish beneficial bacteria in the infant gut and has been studied for its role in early neurodevelopment alongside 3'-SL.
Curious about HMO sourcing and supplement facts? See our full formulation page
HMOs are not for the baby. They are for the bacteria the baby is trying to grow. Specifically, HMOs support the bifidobacteria that dominate the gut of a healthy breastfed infant, with Bifidobacterium infantis being the most studied example. When those bacteria flourish, they produce short-chain fatty acids that help support the gut barrier, support the developing immune system, and support comfortable digestion.
This is what makes a synbiotic different from a probiotic alone. A probiotic introduces beneficial bacteria. A prebiotic feeds them. A synbiotic does both at once, which is what breast milk has been doing for the entire history of human development.
One sachet per day. Mixes into breast milk, formula, water, or soft food.
Shop NurtureBioHMOs work best when paired with the bacteria they are biologically designed to feed.
Selected to represent the major structural classes of HMOs in human milk.
B. infantis, B. bifidum (two strains), and L. reuteri, commonly found in breastfed babies.
Prebiotic plus probiotic in one sachet, formulated for the first four years of life.
NurtureBio is formulated for babies and toddlers ages 0 to 48 months. Families often start using it during feeding transitions, after a round of antibiotics, when introducing solids, or as part of a daily routine that supports gut health from the start.
It mixes easily into breast milk, formula, water, or soft foods, depending on your child's age and what works for your day.
Our Scientific Advisory Board includes Dr. Jim Versalovic, Dr. Ardythe Morrow, Dr. David Newburg, and Dr. Diana Taft. They are among the most cited researchers in human milk and infant microbiome science.
We are conducting clinical research at the University of Cincinnati College of Medicine to advance the science of breast milk and infant gut health.
NurtureBio was started by Stuart and Christina Smith after their son fell from the 30th to the 6th growth percentile and went through five rounds of antibiotics in five months. They could not find a product that took the infant gut microbiome seriously, so they built one with help from leading researchers in the field.
30 sachets. One per day. Mixes into breast milk, formula, water, or soft food.
Free shipping on subscriptions Third-party tested Made in France
Human milk oligosaccharides, or HMOs, are special carbohydrates that make up the third most abundant solid in breast milk after fat and lactose. They are not digested by the baby. Instead, they travel intact to the lower gut where they feed the beneficial bacteria that thrive in the infant microbiome.
NurtureBio includes five HMOs in every sachet: 2'-fucosyllactose, difucosyllactose, lacto-N-tetraose, 3'-sialyllactose, and 6'-sialyllactose. They were selected to represent the major structural classes found in breast milk.
Most modern infant formulas include one or two HMOs as part of their nutritional profile, typically 2'-fucosyllactose. NurtureBio includes five HMOs in a synbiotic format with four probiotic strains. It is designed as a daily supplement that works alongside whatever feeding approach your family uses, whether that is breast milk, formula, or a combination.
A probiotic is a beneficial bacteria. A prebiotic is the food that beneficial bacteria eat. HMOs are a specialized type of prebiotic, naturally abundant in breast milk and uniquely suited to feeding the bacteria found in the infant gut. A synbiotic, which is what NurtureBio is, combines both in one product.
Yes. NurtureBio is formulated to complement breast milk, not replace it. The HMOs and probiotic strains in the product are modeled after what breast milk naturally provides, and many families use it as part of a routine that supports their baby's gut health regardless of feeding method.
Yes. NurtureBio works alongside any feeding approach. It mixes easily into formula, breast milk, water, or soft foods depending on your baby's age.
NurtureBio is formulated for babies and toddlers ages 0 to 48 months.
One sachet per day, mixed into a small amount of breast milk, formula, water, or soft food. For younger babies on milk only, mixing into a small volume of breast milk or formula tends to work best.
HMOs are naturally present in human breast milk and have been part of the human diet for as long as humans have existed. The HMOs used in modern supplements and formulas are produced through precision fermentation and are structurally identical to the HMOs in breast milk. They have been extensively studied for safety in infants.
Every baby is different. Gut health products generally work best with consistent daily use over time. NurtureBio is built as ongoing daily support, not a quick fix.
Call your pediatrician if your baby has fever, vomiting, poor feeding, blood in the stool, persistent crying, signs of dehydration, or a sudden change in behavior. NurtureBio supports daily gut health and is not a substitute for medical care.
Five HMOs, four probiotic strains, one sachet a day. Made for ages 0 to 48 months.
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